In this paper, we developed one-pot facile synthetic approach for preparing fluorescent gold nanoclusters (AuNCs) by utilizing reducing-cum-stabilizing inositol (INOS). The as-prepared INOS protected gold nanoclusters ([email protected]) have excellent monodispersity with uniform size <2.0 nm and exhibit strong inherent fluorescence at 470 nm with a decay time of 12.01 ns. Interestingly, ferric ions (Fe³⁺) can significantly quench the fluorescence of the synthesized [email protected] leading to the efficient Fe³⁺ sensing. On the basis of results obtained from high-resolution transmission electron microscopy (HRTEM), an aggregation-induced fluorescence quenching mechanism was proposed. Based on these fascinating findings, a facile, fast, “green” and highly sensitive AuNCs-dependant fluorescent sensor probe was developed to detect Fe³⁺ ions in water resources and Over-The-Counter (OTC) medicines. Stern-Volmer plot showed a good linear calibration curve for Fe³⁺ assay in the range of 1.0–1000 μM (R² = 0.996) and good precision response to 100.0 μM Fe³⁺ with RSD of 2.94% (n = 3) was also achieved. The obtained limit of detection of 0.54 μM for the determination of Fe³⁺ ions is 10 times lower than the limit value (≈5.5 μM) allowed by the U.S. Environmental Protection Agency in drinkable water, indicating the sensitivity of the fluorescent probe of Fe³⁺ sensing. The excellent selectivity obtained among 16 types of metal ions underpins [email protected] as a promising sensor for real time detection of Fe³⁺ in environmental water samples and pharmaceutical tablets.

在本文中，我们开发了一种利用还原和稳定化肌醇（INOS）制备荧光金纳米团簇（AuNCs）的简便方法。所制备的INOS保护的金纳米团簇（[受电子邮件保护]）具有出色的单分散性，均一尺寸<2.0 nm，并在470 nm处显示强固有荧光，衰减时间为12.01 ns。有趣的是，铁离子（Fe ³⁺）可以显着淬灭合成的[受电子邮件保护]的荧光，从而产生有效的Fe ³⁺感应。基于高分辨率透射电子显微镜（HRTEM）获得的结果，提出了聚集诱导的荧光猝灭机理。基于这些引人入胜的发现，开发了一种便捷，快速，“绿色”且高度敏感的AuNCs依赖性荧光传感器探针，用于检测水资源和非处方（OTC）药物中的Fe ³⁺离子。Stern-Volmer图在1.0–1000μM（R ²  = 0.996）范围内显示出良好的Fe ³⁺测定线性校准曲线，对100.0μMFe ³⁺具有良好的精密度响应，相对标准偏差为2.94％（n = 3）。也实现了。所测Fe ³⁺的检出限为^0.54μM离子比美国环境保护局在饮用水中允许的极限值（≈5.5μM）低10倍，表明Fe ³⁺传感荧光探针的灵敏度。在16种类型的金属离子基柱上获得了优异的选择性（受电子邮件保护），这是一种有前景的传感器，可用于实时检测环境水样品和药物片剂中的Fe ³⁺。