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Autoinflammatory phenotypes in Aicardi-Goutières syndrome with interferon upregulation and serological autoimmune features
Journal of Allergy and Clinical Immunology ( IF 11.4 ) Pub Date : 2017-11-11 , DOI: 10.1016/j.jaci.2017.10.019
Yuji Sugawara , Kohsuke Imai , Ayako Kashimada , Kengo Moriyama , Shimpei Baba , Ryuta Nishikomori , Mizuho Motegi , Yasuo Takeuchi , Tomohiro Morio

In an Aicardi-Goutières syndrome patient, cimetidine successfully controlled periodic fever with improved serum autoimmune marker levels, suggesting the presence of crosstalk between autoinflammation and autoimmunity in type I interferonopathy.



中文翻译:

心律失常综合征的自身炎症性表型,具有干扰素上调和血清自身免疫特征

在Aicardi-Goutières综合征患者中,西咪替丁成功地控制了周期性发烧,同时血清自身免疫标记物水平有所改善,表明I型干扰素病中自体炎症与自身免疫之间存在串扰。

更新日期:2017-11-11
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