We developed a facile method for the synthesis of Gold nanoparticles (AuNPs) stabilized by cationic 1-(3-(acetylthio)propyl)pyrazin-1-ium ligand denoted as APP. Gold nanoparticles stabilized by APP (APP-AuNPs) are found to be polydispersed in size and lie in the range of 5–10 nm. We report a robust and sensitive protocol for the detection of heavy toxic metal ion Pd(II) in water using APP-AuNPs. From the fifteen salts tested, APP-AuNPs demonstrated a sensitive and selective spectrophotometric signal, as well as naked eye indication for recognition of Pd(II) ions. Pd(II) ions caused a colorimetric, distinguished response to APP-AuNPs based on the aggregation induced decrease of surface plasmon resonance (SPR) band. The nanosensor probe displayed a sensitive response to the Pd(II) ions in a wide range of concentration and pH, with detection limit of as low as 4.23 μM. Furthermore, the decrease in SPR band of APP-AuNPs due to Pd(II) ions was unaffected by tap water samples and/or human blood plasma.

我们开发了一种简便的方法，用于合成由阳离子1-（3-（乙酰硫基丙基）丙基吡嗪-1-鎓配体（表示为APP）稳定化的金纳米颗粒（AuNPs）。APP稳定的金纳米颗粒（APP-AuNPs）被发现是大小分散的，在5-10 nm的范围内。我们报告了使用APP-AuNPs检测水中重有毒金属离子Pd（II）的稳健而灵敏的协议。从所测试的15种盐中，APP-AuNPs表现出灵敏且选择性的分光光度信号，以及用于识别Pd（II）离子的肉眼指示。Pd（II）离子基于聚集诱导的表面等离振子共振（SPR）谱带的减少，引起了对APP-AuNPs的比色，显着响应。纳米传感器探针在很宽的浓度和pH范围内显示出对Pd（II）离子的灵敏响应，检出限低至4.23μM。此外，自来水样品和/或人血浆不会影响由于Pd（II）离子引起的APP-AuNPs SPR谱带的下降。