Synthesis ( IF 2.6 ) Pub Date : 2017-11-09 , DOI: 10.1055/s-0036-1590955 Zhen-Jiang Xu 1 , Chi-Ming Che 1, 2 , Yong-Heng Luo 3 , Yuan-Ji Ping 1 , Zong-Rui Li 1 , Xin Gu 1
Abstract
An iron(III)-BPsalan complex was found to efficiently catalyze the asymmetric chlorination reaction of cyclic β-keto esters and N-Boc oxindoles, affording the corresponding chlorinated products in high yield and up to 92% ee with NCS as chlorination reagent under mild reaction conditions.
An iron(III)-BPsalan complex was found to efficiently catalyze the asymmetric chlorination reaction of cyclic β-keto esters and N-Boc oxindoles, affording the corresponding chlorinated products in high yield and up to 92% ee with NCS as chlorination reagent under mild reaction conditions.
中文翻译:
铁(III)-BPsalan配合物催化环状β-酮酯和N-Boc氧化吲哚的不对称氯化反应
摘要
发现铁(III)-BPsalan络合物可有效催化环状β-酮酯和N - Boc羟吲哚的不对称氯化反应,在温和的条件下以NCS作为氯化试剂,可提供高产率和高达92%ee的相应氯化产物。反应条件。
发现铁(III)-BPsalan络合物可有效催化环状β-酮酯和N - Boc羟吲哚的不对称氯化反应,在温和的条件下以NCS作为氯化试剂,可提供高产率和高达92%ee的相应氯化产物。反应条件。