Selenium binds some enzymes such as glutathione peroxidase and thioredoxin reductase, which may be activated in biological infections and oxidative stress. Chemical and physical methods for synthesizing nanoparticles, apart from being expensive, have their own particular risks. However, nanoparticle synthesis through green chemistry is a safe procedure that different biological sources such as bacteria, fungi, yeasts, algae and plants can be the catalyst bed for processing. Synthesis of selenium nanoparticles (SeNPs) by macro/microorganisms causes variation in morphology and shape of the particles is due to diversity of reduction enzymes in organisms. Reducing enzymes of microorganisms by changing the status of redox convert metal ions (Se²⁻) to SeNPs without charge (Se⁰). Biological activity of SeNPs includes their protective role against DNA oxidation. Because of the biological and industrial properties, SeNPs have wide applications in the fields of medicine, microelectronic, agriculture and animal husbandry. SeNPs can show strong antimicrobial effects on the growth and proliferation of microorganisms in a dose-dependent manner. The objective of this review is to consider SeNPs applications to various organisms.

硒结合某些酶，例如谷胱甘肽过氧化物酶和硫氧还蛋白还原酶，这些酶可能在生物感染和氧化应激中被激活。用于合成纳米颗粒的化学和物理方法，除了价格昂贵之外，还有其自身的特殊风险。但是，通过绿色化学合成纳米颗粒是安全的程序，不同的生物来源（例如细菌，真菌，酵母，藻类和植物）可以作为加工的催化剂床。宏观/微生物合成硒纳米粒子（SeNPs）会导致形态和形状变化，这是由于生物体中还原酶的多样性所致。通过改变氧化还原状态将金属离子（Se ²⁻）转换为SeNPs（Se ⁰）来还原微生物的酶）。SeNPs的生物活性包括其对DNA氧化的保护作用。由于其生物学和工业性质，SeNPs在医学，微电子，农业和畜牧业领域具有广泛的应用。SeNP以剂量依赖的方式对微生物的生长和增殖表现出强大的抗菌作用。这篇综述的目的是考虑SeNPs在各种生物中的应用。