Abstract Poly (vinylidene fluoride) (PVDF) based membranes are inert and hydrophobic, which makes them susceptible to biofouling. Blending it with a biopolymer like Poly (butylene succinate-co-adipate) (PBSA) can offer functional sites to tether anti-microbial and anti-fouling agents to improvise the anti-bacterial and anti-fouling properties of PVDF. In this study porous PVDF/PBSA membranes were obtained using non-solvent induced phase separation and modified by a unique phosphonium chloride trihexyltetradecylphosphonium chloride by two approaches. In the first approach; phosphonium chloride was immobilized onto the porous membrane while in the second, the membrane was tethered with graphene oxide initially and then immobilized by phosphonium chloride leading to synergistic performance towards excellent antibacterial and antifouling characteristics. The antimicrobial action manifested by the modifications was assessed by standard plate count taking E.coli and S.aureus as model bacterial organisms. To understand the antimicrobial mechanism, outer membrane permeabilization studies with N-Phenyl-1-naphthylamine assay, intracellular leakage of K+ ion and nucleic acids in metabolic pool and intracellular Reactive oxygen species (ROS) generation studies were assessed. The antifouling study was also carried out by using Bovine serum albumin (BSA) as a model biofoulant. This study demonstrated high distilled water flux, excellent fouling resistance, impressive 7-fold reduction of bacteria and stable flux performance.

中文翻译：

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PVDF/PBSA 膜在表面具有强偶联的鏻衍生物和氧化石墨烯，具有抗菌和防污活性

摘要 基于聚偏二氟乙烯 (PVDF) 的膜具有惰性和疏水性，这使得它们容易受到生物污染。将其与聚（丁二酸丁二醇酯-共-己二酸丁二醇酯）（PBSA）等生物聚合物混合，可以提供功能位点来束缚抗菌剂和防污剂，从而提高 PVDF 的抗菌和防污性能。在这项研究中，多孔 PVDF/PBSA 膜是使用非溶剂诱导相分离获得的，并通过两种方法用独特的氯化鏻三己基十四烷基氯化鏻改性。在第一种方法中；氯化鏻固定在多孔膜上，而在第二个过程中，该膜最初与氧化石墨烯相连，然后由氯化鏻固定，从而产生协同性能，实现优异的抗菌和防污特性。通过以大肠杆菌和金黄色葡萄球菌为模型细菌生物体的标准平板计数来评估由修改表现出的抗微生物作用。为了了解抗菌机制，我们评估了使用 N-Phenyl-1-naphthylamine 测定的外膜透化研究、代谢池中 K+ 离子和核酸的细胞内渗漏以及细胞内活性氧 (ROS) 生成研究。还使用牛血清白蛋白 (BSA) 作为模型生物污染物进行了防污研究。该研究证明了高蒸馏水通量、优异的抗污染性、