Oxidative stress controls regulatory T cell apoptosis and suppressor activity and PD-L1-blockade resistance in tumor,Nature Immunology

当前位置： X-MOL 学术 › Nat. Immunol. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Oxidative stress controls regulatory T cell apoptosis and suppressor activity and PD-L1-blockade resistance in tumor
Nature Immunology ( IF 30.5 ) Pub Date : 2017-10-30 , DOI: 10.1038/ni.3868
Tomasz Maj , Wei Wang , Joel Crespo , Hongjuan Zhang , Weimin Wang , Shuang Wei , Lili Zhao , Linda Vatan , Irene Shao , Wojciech Szeliga , Costas Lyssiotis , J Rebecca Liu , Ilona Kryczek , Weiping Zou

Oxidative stress controls regulatory T cell apoptosis and suppressor activity and PD-L1-blockade resistance in tumor

Oxidative stress controls regulatory T cell apoptosis and suppressor activity and PD-L1-blockade resistance in tumor, Published online: 30 October 2017; doi:10.1038/ni.3868

NatureArticleSnippet(type=short-summary, markup=

The tumor microenvironment represents a stressful cellular environment. Zou and colleagues show that T_reg cells in tumors have heightened sensitivity to apoptosis, but unexpectedly this increases their suppressive potency.

, isJats=true)

中文翻译：