Electrophilic probes for deciphering substrate recognition by O-GlcNAc transferase,Nature Chemical Biology

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Electrophilic probes for deciphering substrate recognition by O-GlcNAc transferase
Nature Chemical Biology ( IF 12.9 ) Pub Date : 2017-10-23 , DOI: 10.1038/nchembio.2494
Chia-Wei Hu , Matthew Worth , Dacheng Fan , Baobin Li , Hao Li , Lei Lu , Xiaofang Zhong , Ziqing Lin , Liming Wei , Ying Ge , Lingjun Li , Jiaoyang Jiang

Electrophilic probes for deciphering substrate recognition by O-GlcNAc transferase

Electrophilic probes for deciphering substrate recognition by O-GlcNAc transferase, Published online: 23 October 2017; doi:10.1038/nchembio.2494

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N-Acetylglucosamine derivatives equipped with electrophilic groups and handles for subsequent chemical tagging are useful probes of substrate recognition by O-GlcNAc transferases and enable the capture of transient protein substrates of these enzymes.

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