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Tumour suppressors: Digging deeper into p53's functions
Nature Reviews Cancer ( IF 72.5 ) Pub Date : 2017-11-10 , DOI: 10.1038/nrc.2017.108
Sarah Seton-Rogers

Tumour suppressors: Digging deeper into p53's functions

Tumour suppressors: Digging deeper into p53's functions, Published online: 10 November 2017; doi:10.1038/nrc.2017.108

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Mello et al. analysed the effects of various p53 transactivation domain mutants in pancreatic ductal adenocarcinoma and uncovered a crucial tumour-suppressive pathway in which p53 mediates inhibition of the transcriptional co-activator YAP.

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中文翻译:

肿瘤抑制器:深入研究p53的功能

肿瘤抑制器:深入研究p53的功能

抑癌剂:深入研究p53的功能,在线发布:2017年11月10日;doi:10.1038 / nrc.2017.108

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梅洛 。分析了各种p53反式激活域突变体在胰腺导管腺癌中的作用,并发现了关键的肿瘤抑制途径,其中p53介导了转录共激活因子YAP的抑制。

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更新日期:2017-11-10
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