当前位置:
X-MOL 学术
›
Photochem. Photobiol. Sci.
›
论文详情
Our official English website, www.x-mol.net, welcomes your
feedback! (Note: you will need to create a separate account there.)
Hydrazine functionalized probes for chromogenic and fluorescent ratiometric sensing of pH and F−: experimental and DFT studies
Photochemical & Photobiological Sciences ( IF 2.7 ) Pub Date : 2017-09-28 00:00:00 , DOI: 10.1039/c7pp00246g Additi Roy Chowdhury 1, 2, 3, 4, 5 , Amita Mondal 1, 2, 3, 4, 6 , Biswajit Gopal Roy 4, 6, 7, 8 , Jagadeesh C. Bose K 4, 9, 10, 11 , Sudit Mukhopadhyay 4, 9, 10, 11 , Priyabrata Banerjee 1, 2, 3, 4, 5
Photochemical & Photobiological Sciences ( IF 2.7 ) Pub Date : 2017-09-28 00:00:00 , DOI: 10.1039/c7pp00246g Additi Roy Chowdhury 1, 2, 3, 4, 5 , Amita Mondal 1, 2, 3, 4, 6 , Biswajit Gopal Roy 4, 6, 7, 8 , Jagadeesh C. Bose K 4, 9, 10, 11 , Sudit Mukhopadhyay 4, 9, 10, 11 , Priyabrata Banerjee 1, 2, 3, 4, 5
Affiliation
Two novel hydrazine based sensors, BPPIH (N1,N3-bis(perfluorophenyl)isophthalohydrazide) and BPBIH (N1′,N3′-bis(perfluorobenzylidene)isophthalohydrazide), are presented here. BPPIH is found to be a highly sensitive pH sensor in the pH range 5.0 to 10.0 in a DMSO–water solvent mixture with a pKa value of 9.22. Interesting optical responses have been observed for BPPIH in the above mentioned pH range. BPBIH on the other hand turns out to be a less effective pH sensor in the above mentioned pH range. The increase in fluorescence intensity at a lower pH for BPPIH was explained by using density functional theory. The ability of BPPIH to monitor the pH changes inside cancer cells is a useful application of the sensor as a functional material. In addition fluoride (F−) selectivity studies of these two chemosensors have been performed and show that between them, BPBIH shows greater selectivity towards F−. The interaction energy calculated from the DFT-D3 supports the experimental findings. The pH sensor (BPPIH) can be further interfaced with suitable circuitry interfaced with desired programming for ease of access and enhancement of practical applications.
中文翻译:
肼官能化的探针用于pH和F的发色和荧光比率传感- :实验和研究DFT
两种新型肼基传感器,BPPIH(Ñ 1,Ñ 3 -双(全氟苯基)isophthalohydrazide)和BPBIH(Ñ 1' ,Ñ 3' -双(perfluorobenzylidene)isophthalohydrazide),在此提出。BPPIH被发现是在pH范围5.0一个高度敏感的pH传感器对在DMSO-水溶剂混合物与AP 10.0 ķ一个的9.22值。在上述pH范围内,对于BPPIH观察到了有趣的光学响应。BPBIH另一方面,在上述pH范围内,pH传感器的效果较差。使用密度泛函理论解释了BPPIH在较低pH值下荧光强度的增加。BPPIH监测癌细胞内pH值变化的能力是传感器作为功能材料的有用应用。在氟除了(F -已执行这两种化学传感器的选择性研究,并表明它们之间)BPBIH对F显示更大的选择性- 。从DFT-D3计算出的相互作用能支持了实验结果。pH传感器(BPPIH可以进一步与合适的电路接口,该合适的电路与期望的编程接口,以便于访问和增强实际应用。
更新日期:2017-11-08
中文翻译:
肼官能化的探针用于pH和F的发色和荧光比率传感- :实验和研究DFT
两种新型肼基传感器,BPPIH(Ñ 1,Ñ 3 -双(全氟苯基)isophthalohydrazide)和BPBIH(Ñ 1' ,Ñ 3' -双(perfluorobenzylidene)isophthalohydrazide),在此提出。BPPIH被发现是在pH范围5.0一个高度敏感的pH传感器对在DMSO-水溶剂混合物与AP 10.0 ķ一个的9.22值。在上述pH范围内,对于BPPIH观察到了有趣的光学响应。BPBIH另一方面,在上述pH范围内,pH传感器的效果较差。使用密度泛函理论解释了BPPIH在较低pH值下荧光强度的增加。BPPIH监测癌细胞内pH值变化的能力是传感器作为功能材料的有用应用。在氟除了(F -已执行这两种化学传感器的选择性研究,并表明它们之间)BPBIH对F显示更大的选择性- 。从DFT-D3计算出的相互作用能支持了实验结果。pH传感器(BPPIH可以进一步与合适的电路接口,该合适的电路与期望的编程接口,以便于访问和增强实际应用。