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Carbon Nanotube as a Tool for Fighting Cancer
Bioconjugate Chemistry ( IF 4.0 ) Pub Date : 2017-11-07 00:00:00 , DOI: 10.1021/acs.bioconjchem.7b00563
Edson José Comparetti , Valber de Albuquerque Pedrosa , Ramon Kaneno

In 2015, cancer was the cause of almost 22% of deaths worldwide. The high frequency of relapsing diseases and metastasis requires the development of new diagnostic and therapeutic approaches, and the use of nanomaterials is a promising tool for fighting cancer. Among the more extensively studied nanomaterials are carbon nanotubes (CNTs), synthesized as graphene sheets, whose spiral shape is varied in length and thickness. Their physicochemical features, such as the resistance to tension, and thermal and electrical conductivity, allow their application in several fields. In this review, we show evidence supporting the applicability of CNTs in biomedical practice as nanocarriers for drugs and immunomodulatory material, emphasizing their potential for use in cancer treatment.

中文翻译:

碳纳米管作为抗癌工具

2015年,癌症是导致全球近22%死亡的原因。复发性疾病和转移的高频率要求开发新的诊断和治疗方法,而纳米材料的使用是抗击癌症的有前途的工具。在更广泛研究的纳米材料中,有合成为石墨烯片的碳纳米管(CNT),其螺旋形状的长度和厚度均不同。它们的物理化学特性(例如抗张强度,导热性和导电性)使其可以在多个领域中应用。在这篇综述中,我们显示了证据支持碳纳米管在生物医学实践中作为药物和免疫调节材料的纳米载体的适用性,强调了其在癌症治疗中的潜力。
更新日期:2017-11-08
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