Green synthesis of α-amino acids by electrochemical carboxylation of imines in a flow microreactor†,Reaction Chemistry & Engineering

当前位置： X-MOL 学术 › React. Chem. Eng. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Green synthesis of α-amino acids by electrochemical carboxylation of imines in a flow microreactor†
Reaction Chemistry & Engineering ( IF 3.4 ) Pub Date : 2017-11-07 00:00:00 , DOI: 10.1039/c7re00149e
Yang Qu _{1,

2,

3,

4} , Chiaki Tsuneishi _{1,

2,

3,

4} , Hiroyuki Tateno _{1,

2,

3,

4} , Yoshimasa Matsumura _{4,

5,

6,

7,

8} , Mahito Atobe _{1,

2,

3,

4}

Affiliation

A new approach for the green synthesis of α-amino acids using electrochemical carboxylation of imines in a flow microreactor is described. This method has the major advantage of not requiring sensitive, expensive, or toxic reagents. In addition, the reaction could be conducted using single flow-through operations, without the need for sacrificial anodes and under very mild and green conditions. Our microreactor system enabled the electrochemical synthesis of N-phenylphenylglycine derivatives in good to moderate yields.

中文翻译：

在流动微反应器中通过亚胺的电化学羧化绿色合成α-氨基酸†

描述了一种在流动微反应器中使用亚胺的电化学羧化绿色合成α-氨基酸的新方法。该方法的主要优点是不需要敏感，昂贵或有毒的试剂。另外，该反应可以使用单一的流通操作进行，而不需要牺牲阳极并且在非常温和和绿色的条件下进行。我们的微反应器系统使N-苯基苯基甘氨酸衍生物能够以良好至中等的产率进行电化学合成。

更新日期：2017-11-07

点击分享查看原文

点击收藏

阅读更多本刊最新论文本刊介绍/投稿指南11