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A new lead to NLRP3 inhibition
Journal of Experimental Medicine ( IF 12.6 ) Pub Date : 2017-11-06 , DOI: 10.1084/jem.20171848 Mohamed Lamkanfi 1 , Vishva M. Dixit 1
中文翻译:
抑制NLRP3的新方法
更新日期:2017-11-06
Journal of Experimental Medicine ( IF 12.6 ) Pub Date : 2017-11-06 , DOI: 10.1084/jem.20171848 Mohamed Lamkanfi 1 , Vishva M. Dixit 1
Affiliation
The discovery of a small molecule inhibitor that targets the inflammasome sensor NLRP3 offers a new path for the development of selective inflammasome blockers with potential therapeutic benefit in a wide range of human diseases (in this issue, see Jiang et al., https://doi.org/10.1084/jem.20171419).
中文翻译:
抑制NLRP3的新方法
靶向炎性体传感器NLRP3的小分子抑制剂的发现为开发选择性炎性体阻滞剂提供了一条新途径,该阻滞剂在多种人类疾病中均具有潜在的治疗益处(在本期中,请参见Jiang等人,https:// doi.org/10.1084/jem.20171419)。