Quinone-based fluorophores for imaging biological processes,Chemical Society Reviews

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Quinone-based fluorophores for imaging biological processes
Chemical Society Reviews ( IF 40.4 ) Pub Date : 2017-11-03 00:00:00 , DOI: 10.1039/c7cs00553a
Gleiston G. Dias _{1,

2,

3,

4,

5} , Aaron King _{6,

7,

8,

9} , Fabio de Moliner _{6,

7,

8,

9} , Marc Vendrell _{6,

7,

8,

9} , Eufrânio N. da Silva Júnior _{1,

2,

3,

4,

5}

Affiliation

Quinones are privileged chemical structures playing crucial roles as redox and alkylating agents in a wide range of processes in cells. The broad functional array of quinones has prompted the development of new chemical approaches, including C–H bond activation and asymmetric reactions, to generate probes for examining their activity by means of fluorescence imaging. This tutorial review covers recent advances in the design, synthesis and applications of quinone-based fluorescent agents for visualizing specific processes in multiple biological systems, from cells to tissues and complex organisms in vivo.

中文翻译：

用于生物过程成像的基于醌的荧光团

醌是特权化学结构，在细胞的广泛过程中起氧化还原和烷基化剂的作用。广泛的醌功能促进了新化学方法的开发，包括C–H键激活和不对称反应，从而产生了用于通过荧光成像检查其活性的探针。本教程概述涵盖了基于醌的荧光剂的设计，合成和应用方面的最新进展，用于可视化多种生物系统（从细胞到组织以及体内复杂生物）中的特定过程。

更新日期：2017-11-03

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