The first palladium-catalyzed diastereoselective conjugate addition of arylboronic acids to chiral imides is reported. The catalytic system employing 4-tert-butyloxazolidin-2-one as the chiral auxiliary in a mixed solvent system of MeOH/H₂O (1:3) under an air atmosphere provides the optically active 3-arylbutanoic acid derivatives in excellent yields with high diastereoselectivity.

中文翻译：

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钯催化的3-芳基丁酸衍生物的非对映选择性合成

据报道，芳基硼酸第一次钯催化的非对映选择性共轭加成到手性酰亚胺上。在空气气氛下，在MeOH / H ₂ O（1：3）混合溶剂体系中，以4-叔丁基恶唑烷-2-酮为手性助剂的催化体系提供了具有优异收率的旋光性3-芳基丁酸衍生物。高非对映选择性。