当前位置: X-MOL 学术Cancer Discov. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Mutation Load Offers Biomarker in SCLC
Cancer Discovery ( IF 29.7 ) Pub Date : 2017-12-01 , DOI: 10.1158/2159-8290.cd-nb2017-154
American Association for Cancer Research

Tumor mutation burden offers a promising predictive biomarker for patients with small cell lung cancer. An exploratory analysis presented at the World Conference on Lung Cancer showed that the patients with large numbers of mutations in their cancer cells were more likely to respond—and for a longer time—to a single checkpoint inhibitor or a combination of them than those with a low mutation load.



中文翻译:

突变负载在SCLC中提供生物标记

肿瘤突变负担为小细胞肺癌患者提供了有希望的预测性生物标志物。在世界肺癌大会上进行的一项探索性分析表明,癌细胞中具有大量突变的患者对单检查点抑制剂或它们的组合的反应比对那些接受检查的抑制剂更可能(更长的时间)。突变负荷低。

更新日期:2017-12-05
down
wechat
bug