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Anti-HIV Passive Immunization: New Weapons in the Arsenal
Trends in Microbiology ( IF 14.0 ) Pub Date : 2017-10-30 , DOI: 10.1016/j.tim.2017.10.006
Ruth M. Ruprecht

Anti-HIV passive immunization with human neutralizing monoclonal antibodies (nmAbs) has made exciting gains: (i) identification of the HIV envelope V2 apex as a new in vivo protective epitope, (ii) a novel clade C SHIV for challenge studies, and (iii) a highly protective, trispecific nmAb. Potent, broad-spectrum protection by nmAbs holds promise.



中文翻译:

抗艾滋病毒被动免疫:武器库中的新武器

人类中和性单克隆抗体(nmAbs)的抗HIV被动免疫取得了令人兴奋的进展:(i)将HIV包膜V2顶点鉴定为一种新的体内保护性表位,(ii)用于攻击研究的新型C SHIV进化枝,和( iii)具有高度保护性的三特异性nmAb。nmAbs的强效,广谱保护前景广阔。

更新日期:2017-10-30
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