Two-dimensional (2D) graphene-like nanomaterials show wide applications in the fields of nanodevices, sensors, energy materials, catalysis, drug delivery, bioimaging, and tissue engineering. Recently, many studies have been focused on the synthesis and application of 2D transition metal dichalcogenide (TMD) nanosheets for various biomedical applications. In particular, 2D TMD nanosheets exhibit great advantages for tumor imaging and therapy compared to some traditional nanomaterials due to their high specific surface area, good biocompatibility, easy modification, and ultrahigh light and heat conversion efficiency. In this review, we summarize the recent advances in the synthesis, modification, and photo/thermo-based tumor imaging and therapy of 2D TMD nanosheets. The important studies on tumor bioimaging with TMD nanosheets, such as X-ray computed tomography, magnetic resonance imaging, and photoacoustic imaging, are demonstrated and discussed. In another section, the physical photothermal and photodynamic therapies as well as the pharmacological therapy of tumors with TMD nanosheet-based nanohybrids are introduced. It is expected that this work will be valuable for readers to understand the synthesis and modification of TMD nanosheets to design novel 2D functional nanomaterials for photo/thermo-based tumor imaging and therapy in one aspect, and in another aspect will extend the applications of TMD-based nanomaterials in materials science, analytical science, electrocatalysis, tissue engineering, and others.

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用于基于光/热的肿瘤成像和治疗的2D过渡金属二硫化二氢纳米片

二维（2D）类石墨烯纳米材料在纳米器件，传感器，能源材料，催化，药物输送，生物成像和组织工程领域中显示出广泛的应用。近来，许多研究集中在用于各种生物医学应用的2D过渡金属二卤化二硫化碳（TMD）纳米片的合成和应用上。特别地，由于2D TMD纳米片具有高的比表面积，良好的生物相容性，易于修饰以及超高的光和热转换效率，因此与某些传统的纳米材料相比，在肿瘤成像和治疗方面显示出巨大的优势。在这篇综述中，我们总结了二维TMD纳米片的合成，修饰和基于光/热的肿瘤成像和治疗的最新进展。TMD纳米片对肿瘤生物显像的重要研究，诸如X射线计算机断层扫描，磁共振成像和光声成像等演示和讨论。在另一部分中，介绍了基于TMD纳米片的纳米杂化物的物理光热疗法和光动力疗法以及肿瘤的药理疗法。期望这项工作对于读者理解TMD纳米片的合成和修饰，以设计新颖的2D功能纳米材料用于基于光/热的肿瘤成像和治疗的有价值的研究，在另一方面将扩展TMD的应用。材料科学，分析科学，电催化，组织工程等领域的基于纳米的材料。介绍了基于TMD纳米片的纳米杂化物的物理光热和光动力疗法以及肿瘤的药理疗法。期望这项工作对于读者理解TMD纳米片的合成和修饰，以设计新颖的2D功能纳米材料用于基于光/热的肿瘤成像和治疗的有价值的研究，在另一方面将扩展TMD的应用。材料科学，分析科学，电催化，组织工程等领域的基于纳米的材料。介绍了基于TMD纳米片的纳米杂化物的物理光热和光动力疗法以及肿瘤的药理疗法。期望这项工作对于读者理解TMD纳米片的合成和修饰，以设计新颖的2D功能纳米材料用于基于光/热的肿瘤成像和治疗的有价值的研究，在另一方面将扩展TMD的应用。材料科学，分析科学，电催化，组织工程等领域的基于纳米的材料。