10 gram-scale synthesis of a chiral oxazoline iminopyridine ligand and its applications,Organic Chemistry Frontiers

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10 gram-scale synthesis of a chiral oxazoline iminopyridine ligand and its applications
Organic Chemistry Frontiers ( IF 4.6 ) Pub Date : 2017-10-20 00:00:00 , DOI: 10.1039/c7qo00816c
Jianhui Chen _{1,

2,

3,

4} , Tuo Xi _{1,

2,

3,

4} , Zhan Lu _{1,

2,

3,

4}

Affiliation

This method reports on the preparation of the chiral oxazoline iminopyridine (OIP) ligand and its applications in the asymmetric hydroboration and hydrosilylation of 1,1-disubstituted alkenes. These reactions could be carried out on a scale of 10 grams.

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