Column chromatographic methods have been developed to separate no-carrier-added 111Ag from proton irradiated thorium targets and associated fission products as an ancillary process to an existing 225Ac separation design. Herein we report the separation of 111Ag both prior and subsequent to 225Ac recovery using CL resin, a solvent impregnated resin (SIR) that carries an organic solution of alkyl phosphine sulfides (R3P = S) and alkyl phosphine oxides (R3P = O). The recovery yield of 111Ag was 93 ± 9% with a radiochemical purity of 99.9% (prior) and 87 ± 9% with a radiochemical purity of 99.9% (subsequent to) 225Ac recovery. Both processes were successfully performed with insignificant impacts on 225Ac yields or quality. Measured equilibrium distribution coefficients for silver and ruthenium (a residual contaminant) on CL resin in hydrochloric and nitric acid media are reported, to the best of our knowledge, for the first time. Additionally, measured cross sections for the production of 111Ag and 110mAg for the 232Th(p,f)110m,111Ag reactions are reported within.

中文翻译：

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从质子辐照的钍基质中分离出治疗诊断放射性核素 111 Ag

已经开发出柱色谱方法，将未添加载体的 111Ag 从质子辐照的钍靶和相关裂变产物中分离出来，作为现有 225Ac 分离设计的辅助过程。在此，我们报告了使用 CL 树脂在 225Ac 回收之前和之后分离 111Ag，CL 树脂是一种溶剂浸渍树脂 (SIR)，带有烷基硫化膦 (R3P = S) 和烷基氧化膦 (R3P = O) 的有机溶液。111Ag 的回收率为 93±9%，放射化学纯度为 99.9%（之前），225Ac 回收率为 87±9%，放射化学纯度为 99.9%（之后）。这两个过程都成功进行，对 225Ac 的产量或质量影响不大。据我们所知，这是首次报道了在盐酸和硝酸介质中 CL 树脂上银和钌（一种残留污染物）的平衡分布系数的测量值。此外，其中还报告了用于 232Th(p,f)110m,111Ag 反应产生 111Ag 和 110mAg 的测量横截面。