A polymeric carrier containing a naphthalene and iridium(III) complex was developed to deliver extracellular singlet oxygen (¹O₂) into cancer cells to induce oxidative damage without intracellular O₂ consumption. The release of ¹O₂ was triggered by the photothermal effect of Au nanorods upon irradiation at 808 nm, realizing controllable therapy combining both oxidative and photothermal damage.

中文翻译：

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光热触发从含内过氧化物的聚合物载体中释放单重态氧以杀死癌细胞

开发了一种包含萘和铱（III）配合物的聚合物载体，可以将细胞外单线态氧（¹ O ₂）输送到癌细胞中，从而诱导氧化损伤，而无需消耗细胞内O ₂。的释放¹ Ò ₂用的Au纳米棒的照射时的光热效应在808纳米触发，实现可控的疗法结合两种氧化和光热损伤。