Isolation and characterization of urinary extracellular vesicles: implications for biomarker discovery

Nature Reviews Nephrology, Published online: 30 October 2017; doi:10.1038/nrneph.2017.148

Extracellular vesicles in the urine have potential as disease biomarkers. This Review discusses the different types of extracellular vesicles and the optimization of approaches to enable their isolation and purification, and to characterize their composition by high-throughput 'omics' technologies.

中文翻译：

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尿液细胞外囊泡的分离和表征：对生物标志物发现的启示

尿液细胞外囊泡的分离和表征：对生物标志物发现的启示

Nature Reviews Nephrology，在线发布：2017年10月30日；doi：10.1038 / nrneph.2017.148

尿液中的细胞外囊泡有可能成为疾病的生物标志物。这篇综述讨论了不同类型的细胞外囊泡，以及使它们能够分离和纯化并通过高通量“组学”技术表征其组成的方法的优化。