Preribosomes escaping from the nucleus are caught during translation by cytoplasmic quality control

Nature Structural & Molecular Biology, Published online: 30 October 2017; doi:10.1038/nsmb.3495

Abnormal pre-60S particles are able to escape nuclear quality control and join mature 40S subunits to catalyze cytoplasmic protein synthesis, but the resulting translation defects trigger the cytoplasmic surveillance machineries RQC and the Ski-exosome.

中文翻译：

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从胞核逃逸的核糖体在翻译过程中被细胞质质量控制捕获

从胞核逃逸的核糖体在翻译过程中被细胞质质量控制捕获

《自然结构与分子生物学》，在线发布：2017年10月30日；doi：10.1038 / nsmb.3495

60S之前的异常颗粒能够逃脱核质控制，并加入成熟的40S亚基来催化细胞质蛋白的合成，但由此产生的翻译缺陷触发了细胞质监视机制RQC和Ski-exosome。