Metal-organic frameworks (MOFs) as a subclass of coordination polymers, have attracted wide interest in various field. Herein, we focus on its application in chromatographic separation due to its excellent physical and chemical properties such as large surface area, high porosity, uniform pore sizes and structural diversity. In 2014, a review was published to summarize the most significant advances in MOFs, and their applications in separation science. The present review was an extensive update on applications of MOFs in chromatographic separation from 2014 to the present such as high-performance liquid chromatography (HPLC), capillary electrochromatography (CEC), nano-liquid chromatography (nano-LC), and gas chromatography (GC). Besides, the typical applications of MOFs in solid-phase microextraction (SPME) were also discussed. Except the presentation of experimental data, the limitations and prospects were also summarized in this review, which can offer an outlook and reference on further study of applications of MOFs.

金属有机骨架（MOFs）作为配位聚合物的一个子类，引起了各个领域的广泛兴趣。本文中，由于其出色的物理和化学特性（例如大表面积，高孔隙率，均匀的孔径和结构多样性），我们专注于其在色谱分离中的应用。2014年，发表了一篇综述，总结了MOF的最重大进展及其在分离科学中的应用。本综述是从2014年至今MOF在色谱分离中的应用的广泛更新，例如高效液相色谱（HPLC），毛细管电色谱（CEC），纳米液相色谱（nano-LC）和气相色谱（ GC）。此外，还讨论了MOF在固相微萃取（SPME）中的典型应用。