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Metabolomics as a tool to identify biomarkers to predict and improve outcomes in reproductive medicine: a systematic review
Human Reproduction Update ( IF 13.3 ) Pub Date : 2017-08-08 , DOI: 10.1093/humupd/dmx023
Timothy Bracewell-Milnes , Srdjan Saso , Hossam Abdalla , Dimitrios Nikolau , Julian Norman-Taylor , Mark Johnson , Elaine Holmes , Meen-Yau Thum

Infertility is a complex disorder with significant medical, psychological and financial consequences for patients. With live-birth rates per cycle below 30% and a drive from the Human Fertilisation and Embryology Authority (HFEA) to encourage single embryo transfer, there is significant research in different areas aiming to improve success rates of fertility treatments. One such area is investigating the causes of infertility at a molecular level, and metabolomics techniques provide a platform for studying relevant biofluids in the reproductive tract.

中文翻译:

代谢组学作为鉴定生物标志物以预测和改善生殖医学结果的工具:系统综述

不孕症是一种复杂的疾病,对患者具有重大的医学,心理和财务后果。由于每个周期的活产率低于30%,并且人类受精和胚胎学管理局(HFEA)鼓励鼓励单胚胎移植,因此在不同领域进行了大量研究,旨在提高生育治疗的成功率。一个这样的领域正在分子水平上研究不育的原因,而代谢组学技术为研究生殖道中相关生物流体提供了一个平台。
更新日期:2017-10-27
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