Organoids: Modelling polycystic kidney disease

Nature Materials, Published online: 25 October 2017; doi:10.1038/nmat5013

Cysts were generated from organoids in vitro and the removal of adherent cues was shown to play a key role in polycystic kidney disease progression. These cysts resembled those of diseased tissue phenotypically and were capable of remodelling their microenvironment.

中文翻译：

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类器官：模拟多囊肾

类器官：模拟多囊肾

《自然材料》（Nature Materials），在线发布：2017年10月25日; doi：10.1038 / nmat5013

囊肿是由类器官在体外产生的，粘附信号的去除在多囊肾疾病的进展中起关键作用。这些囊肿在表型上类似于患病组织的囊肿，并且能够重塑其微环境。