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Natural killer cells migrate into and control simian immunodeficiency virus replication in lymph node follicles in African green monkeys
Nature Medicine ( IF 58.7 ) Pub Date : 2017-10-16 , DOI: 10.1038/nm.4421
Nicolas Huot , Beatrice Jacquelin , Thalia Garcia-Tellez , Philippe Rascle , Mickaël J Ploquin , Yoann Madec , R Keith Reeves , Nathalie Derreudre-Bosquet , Michaela Müller-Trutwin

Natural killer cells migrate into and control simian immunodeficiency virus replication in lymph node follicles in African green monkeys

Nature Medicine, Published online: 16 October 2017; doi:10.1038/nm.4421

Huot et al. investigate the differences in natural killer (NK) cells in lymph nodes during pathogenic and nonpathogenic simian immunodeficiency virus (SIV) infection of cynomolgus macaques and African green monkeys (AGMs), respectively. Their findings suggest that NK cells are specifically recruited to follicles in AGMs and regulate SIV replication in the lymph node.



中文翻译:

自然杀伤细胞迁移并控制猿猴免疫缺陷病毒在非洲绿猴的淋巴结滤泡中复制

自然杀伤细胞迁移并控制猿猴免疫缺陷病毒在非洲绿猴的淋巴结滤泡中复制

《自然医学》(Nature Medicine),在线发布:2017年10月16日; doi:10.1038 / nm.4421

Huot。分别研究了食蟹猕猴和非洲绿猴(AGM)的致病性和非致病性猿猴免疫缺陷病毒(SIV)感染过程中淋巴结中自然杀伤(NK)细胞的差异。他们的发现表明,NK细胞被专门募集到AGM中的卵泡,并调节SIV在淋巴结中的复制。

更新日期:2017-10-25
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