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Sympathetic neuron–associated macrophages contribute to obesity by importing and metabolizing norepinephrine
Nature Medicine ( IF 58.7 ) Pub Date : 2017-10-09 , DOI: 10.1038/nm.4422
Roksana M Pirzgalska , Elsa Seixas , Jason S Seidman , Verena M Link , Noelia Martínez Sánchez , Inês Mahú , Raquel Mendes , Vitka Gres , Nadiya Kubasova , Imogen Morris , Bernardo A Arús , Chelsea M Larabee , Miguel Vasques , Francisco Tortosa , Ana L Sousa , Sathyavathy Anandan , Erin Tranfield , Maureen K Hahn , Matteo Iannacone , Nathanael J Spann , Christopher K Glass , Ana I Domingos

Sympathetic neuron–associated macrophages contribute to obesity by importing and metabolizing norepinephrine

Nature Medicine, Published online: 9 October 2017; doi:10.1038/nm.4422

Sympathetic neuron–associated macrophages act as a local sink for norepinephrine, leading to reduced thermogenesis and increased obesity.



中文翻译:

交感神经元相关的巨噬细胞通过输入和代谢去甲肾上腺素促进肥胖

交感神经元相关的巨噬细胞通过输入和代谢去甲肾上腺素促进肥胖

《自然医学》(Nature Medicine),在线发布:2017年10月9日; doi:10.1038 / nm.4422

交感神经元相关的巨噬细胞充当去甲肾上腺素的局部吸收区,导致生热减少和肥胖增加。

更新日期:2017-10-25
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