Background

The links between gut microbiota and obesity are complex and multidirectional. A large number of studies have demonstrated the provoking effect of microbiota as the main environmental factor on the metabolic, and physiology status of its human host, as well as energy harvest. Dietary compounds are a source of energy and metabolites for gut bacteria. Dietary compounds also change the composition of gut microbiota and can influence the production of their metabolites. Impact of intestinal microbiota composition and metabolic interaction, including interaction with dietary components are the key issue in human health and obesity.

Scope and approach

Gut microecology could help fulfill the gap between obesity and energy intake throughout altering the processing of nutrients and energy storage in the body, revealing diet-related and age-related changes in the human intestinal microbiome and their consequences. Therefore, it is of critical importance in the prevention of obesity to understand how different types of food can influence gut mucosal integrity.

Key findings and conclusions

The association between gut microbiota and host metabolism could help explain promising therapeutic approaches throughout gut microbiota regulation in preventing and treating obesity.

中文翻译：

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肠道菌群，饮食化合物和肥胖症之间有关系吗？

背景

肠道菌群与肥胖之间的联系是复杂且多方向的。大量研究表明，作为主要环境因素的微生物群对其人宿主的代谢，生理状况以及能量收集具有刺激性。饮食化合物是肠道细菌的能量和代谢产物。膳食化合物还会改变肠道菌群的组成，并可能影响其代谢产物的产生。肠道菌群组成和代谢相互作用（包括与饮食成分的相互作用）的影响是人类健康和肥胖症的关键问题。

范围和方法

肠道微生态学可以通过改变体内营养物质和能量存储的过程来帮助解决肥胖与能量摄入之间的差距，揭示人类肠道微生物组与饮食有关和与年龄有关的变化及其后果。因此，了解不同类型的食物如何影响肠道粘膜完整性对于预防肥胖至关重要。

主要发现和结论

肠道菌群与宿主代谢之间的关联可以帮助解释在预防和治疗肥胖症中贯穿整个肠道菌群调控的有前途的治疗方法。