The use of lateral flow assays exploiting antibodies is well established in different fields due to their advantages, which include low cost, ease of production and rapid response, with the only required end-user intervention being sample addition. In recent years, aptamer-based lateral flow assays are garnering increasing interest offering a highly cost-effective and more flexible alternative to antibodies. In this review, an overview of the aptamer-based lateral flow assays developed to date is provided, highlighting the advantages of using aptamers and their ability to be incorporated into formats not possible with antibodies.

中文翻译：

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基于适体的侧向流动测定技术的进展

由于抗体的优势，包括低成本，易于生产和快速响应，因此利用抗体的侧流测定法在不同领域已得到广泛应用，最终用户只需干预即可添加样品。近年来，基于适体的侧向血流分析越来越引起人们的兴趣，它们提供了一种成本效益更高且更灵活的抗体替代品。在这篇综述中，提供了迄今为止开发的基于适体的侧向流测定法的概述，突出了使用适体的优势及其将其并入抗体无法实现的形式的能力。