Environmental and health studies of arsenic require the determination of arsenic species of diverse properties and toxicities. This review summarizes recent analytical advances in speciation of phenylarsenicals. Arsenic speciation techniques have taken advantage of high performance liquid chromatography (HPLC) separation with inductively coupled plasma mass spectrometry (ICPMS) and electrospray ionization tandem mass spectrometry (ESI-MS/MS) detection. These techniques have enabled the identification and quantitation of new arsenic species. Characterization of phenylarsenical metabolites has contributed to better understanding of the fate of phenylarsenicals and the potential risk of human exposure. Binding of trivalent phenylarsenicals to proteins has facilitated the development of analytical techniques for the capture and identification of arsenic-binding proteins.

砷的环境和健康研究要求确定各种性质和毒性的砷物种。这篇综述总结了苯基砷化物形态的最新分析进展。砷形态分析技术利用了高效液相色谱（HPLC）分离，电感耦合等离子体质谱（ICPMS）和电喷雾电离的优势串联质谱（ESI-MS / MS）检测。这些技术使得能够鉴定和定量新的砷物种。苯砷代谢物的表征有助于更好地了解苯砷的命运以及人类暴露的潜在风险。三价苯基砷与蛋白质的结合促进了捕获和鉴定砷结合蛋白的分析技术的发展。