A novel surface plasmon resonance (SPR) optical fiber biosensor, able to bind perfluorooctanoate and perfluorooctanesulfonate compounds, is presented. In the first step, an ad hoc antibody compound has been designed, produced and tested by ELISA, then, in the second step, the gold surface of a plastic optical fiber sensor has been derivatizated and functionalized with this new bio-receptor, able to bind target analytes with high affinity and selectivity. The experimental data have shown that the developed SPR optical fiber biosensor makes it possible to detect these compounds. One advantage of this approach stems from the possibility to monitor the perfluorinated compounds in the environment exploiting the remote sensing capability offered by the optical fibers. The measurements were performed in laboratory, also exploiting matrices mimicking the real environment. The limit of detection of the assay was 0.21 ppb, a value that is lower than the maximum residue limit fixed by the European Union regulations.

提出了一种新型的能够结合全氟辛酸酯和全氟辛烷磺酸化合物的表面等离振子共振（SPR）光纤生物传感器。第一步，通过ELISA设计，生产和测试了一种临时抗体化合物，然后，在第二步中，使用这种新型生物受体衍生了塑料光纤传感器的金表面并对其进行了功能化，从而能够以高亲和力和选择性结合目标分析物。实验数据表明，开发的SPR光纤生物传感器使检测这些化合物成为可能。这种方法的一个优势来自利用光纤提供的遥感功能来监视环境中全氟化合物的可能性。测量是在实验室进行的，还利用模仿真实环境的矩阵。该检测方法的检出限为0.21 ppb，该值低于欧盟法规规定的最大残留限量。