A 10-year-old girl, affected by acute myeloid leukaemia who developed pulmonary aspergillosis after bone marrow transplant, underwent a contrast-enhanced chest computed tomography. The scan showed bilateral pulmonary consolidations and left pleural effusion, consistent with the known infection. In the delayed post-contrast acquisitions, two ring-enhancing lesions with a hypodense central core were also noted within the left ventricular myocardium, at the mid-apical antero-lateral and inferior walls, respectively (Panel A, arrows). After 2 weeks of antifungal treatment, a cardiac magnetic resonance imaging scan was performed for further myocardial lesions characterization. The functional and morphologic sequences acquired before contrast administration showed mild to no myocardial abnormalities; in particular, a faint hyperintensity of the inferior wall on black-blood fat-saturated T2-weighted images (Panel B, dashed circle) was noted. No significant findings were demonstrated at black-blood T1-weighted acquisitions and at SSFP cine images. Overall the conventional pre contrast sequences didn’t show a significant fungal myocardial involvement, suggesting an optimal response to treatment. On the contrary, the native T1-mapping (Panel C, arrows) clearly showed the two known myocardial lesions, with significantly increased T1 values (around 1150 ms).

中文翻译：

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天然T1定位在心脏曲霉病组织表征中的附加价值

一名患有急性髓细胞性白血病的10岁女孩在骨髓移植后发展为肺曲霉病，接受了胸部增强X线断层扫描。扫描显示双侧肺部固结和左胸腔积液，与已知感染一致。在延迟的造影后采集中，在左心室心肌中，在心尖前外侧壁和下壁分别发现了两个中心核密度低的环形增强病变（图A，箭头））。抗真菌治疗2周后，进行了心脏磁共振成像扫描以进一步表征心肌病变。对比剂给药前获得的功能和形态序列显示轻度至无心肌异常；特别是，在黑色血脂饱和的T2加权图像（图B，虚线圆圈）上，下壁出现了微弱的高信号。在黑血T1加权采集和SSFP电影图像中，没有发现明显的发现。总体而言，常规对比前序列未显示出明显的真菌心肌受累，提示对治疗的最佳反应。相反，原生T1映射（图C，箭头）清楚地显示出两个已知的心肌病变，T1值显着增加（约1150 ms）。