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Nanoscale Imaging Reveals Big Role for Iron in Alzheimer’s Disease
Cell Chemical Biology ( IF 6.6 ) Pub Date : 2017-10-19 , DOI: 10.1016/j.chembiol.2017.10.002
Scott Ayton , Simon A. James , Ashley I. Bush

In this issue ofCell Chemical Biology,Telling et al. (2017)apply advanced X-ray microscopy techniques to reveal magnetite iron species in plaques from a mouse model of Alzheimer’s disease. The characterization of abnormal iron chemistry in the disease model highlights the potential for iron to combine with the β-amyloid peptide and accelerate the disease process.

中文翻译:

纳米成像揭示铁在阿尔茨海默氏病中的重要作用

在本期《细胞化学生物学》中,Telling等人。(2017)应用先进的X射线显微镜技术揭示了阿尔茨海默氏病小鼠模型的斑块中的磁铁矿物质。疾病模型中铁化学异常的特征突出了铁与β淀粉样肽结合并加速疾病进程的潜力。
更新日期:2017-12-14
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