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Transforming Lipoxygenases: PE-Specific Enzymes in Disguise.
Cell ( IF 45.5 ) Pub Date : 2017-Oct-19 , DOI: 10.1016/j.cell.2017.10.006
Ling F. Ye , Brent R. Stockwell

In this issue of Cell, Wenzel et al. solve a long-standing mystery regarding how damage to cell membranes occurs during ferroptosis, an iron-dependent form of regulated cell death. They found that lipoxygenases are like Transformer toys, being converted from one enzyme type to another in the presence of the protein PEBP1.

中文翻译:

转化脂氧合酶:伪装成PE的特定酶。

在本期《细胞》中,Wenzel等人。解决了长期存在的谜团,即铁素体病(一种依赖铁的形式的受调节的细胞死亡)是如何在细胞膜受损的情况下发生的。他们发现脂加氧酶就像变形金刚玩具一样,在存在蛋白质PEBP1的情况下从一种酶转变为另一种酶。
更新日期:2017-10-19
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