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Bioluminescence Resonance Energy Transfer (BRET)-coupled Annexin V-functionalized Quantum Dots for Near-Infrared Optical Detection of Apoptotic Cells
ChemBioChem ( IF 3.2 ) Pub Date : 2017-10-18 08:05:32 , DOI: 10.1002/cbic.201700486
Setsuko Tsuboi 1 , Takashi Jin 1
Affiliation  

BRETter detection: Deregulation in apoptosis induces numerous diseases such as cancer, cardiovascular, and neurodegenerative diseases. Detection of apoptotic cells is crucial for understanding the mechanism of those diseases and for therapeutic development. We report near-infrared optical detection of apoptotic cells using BRET-coupled annexin V-functionalized CdSeTe/CdS quantum dots.

中文翻译:

生物发光共振能量转移(BRET)偶联膜联蛋白V功能化的量子点的凋亡细胞的近红外光学检测。

BRETter检测:细胞凋亡的失调会诱发许多疾病,例如癌症,心血管疾病和神经退行性疾病。检测凋亡细胞对于了解这些疾病的机制和治疗发展至关重要。我们报告了使用BRET偶联膜联蛋白V功能化的CdSeTe / CdS量子点的凋亡细胞的近红外光学检测。
更新日期:2017-10-18
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