A Chemoenzymatic Histology Method for O‐GlcNAc Detection,ChemBioChem

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A Chemoenzymatic Histology Method for O‐GlcNAc Detection
ChemBioChem ( IF 2.6 ) Pub Date : 2017-12-05 , DOI: 10.1002/cbic.201700515
Aime Lopez Aguilar ₁ , Xiaomeng Hou ₁ , Liuqing Wen ₂ , Peng G Wang ₂ , Peng Wu ₁

Affiliation

O‐GlcNAcylation dynamically impacts multiple biological processes: We developed a chemoenzymatic histology method for O‐GlcNAc detection and applied it to examine O‐GlcNAcylation in tissue specimens from healthy donors and patients. Specific O‐GlcNAc distribution patterns were uncovered, underlining the utility of this method for studying O‐GlcNAc biology in physiopathological processes.

中文翻译：

O-GlcNAc 检测的化学酶组织学方法

O-GlcNAc 动态影响多种生物过程：我们开发了一种用于 O-GlcNAc 检测的化学酶组织学方法，并将其应用于检查健康供体和患者组织标本中的 O-GlcNAc 化。特定的 O-GlcNAc 分布模式被发现，强调了该方法在研究病理生理过程中 O-GlcNAc 生物学方面的实用性。

更新日期：2017-12-05

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