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Synthesis of Anisotropic Hydrogels and Their Applications
Angewandte Chemie International Edition ( IF 16.1 ) Pub Date : 2018-01-10 , DOI: 10.1002/anie.201708196
Koki Sano 1, 2 , Yasuhiro Ishida 2 , Takuzo Aida 1, 2
Affiliation  

Owing to their water‐rich structures, which are similar to those of biological tissues, hydrogels have long been regarded as promising scaffolds for artificial tissues and organs. However, in terms of the structural anisotropy, most synthetic hydrogels are substantially different from biological systems. Synthetic hydrogels are usually composed of randomly oriented three‐dimensional polymer networks whereas biological systems adopt anisotropic structures with hierarchically integrated building units. Such anisotropic structures often play essential roles in biological systems to exhibit particular functions. In this context, anisotropic hydrogels provide an entry point for exploring biomimetic applications of hydrogels. Reflecting these aspects, an increasing number of studies on anisotropic hydrogels have been reported recently. This Minireview highlights the use and perspectives of these anisotropic hydrogels, particularly focusing on their preparation, structures, and applications.

中文翻译:

各向异性水凝胶的合成及其应用

由于其与生物组织相似的富水结构,水凝胶长期以来被认为是用于人造组织和器官的有前途的支架。但是,就结构各向异性而言,大多数合成水凝胶与生物系统有很大不同。合成水凝胶通常由随机定向的三维聚合物网络组成,而生物系统采用具有分层集成建筑单元的各向异性结构。这样的各向异性结构通常在生物系统中发挥重要作用以表现出特定的功能。在这种情况下,各向异性水凝胶为探索水凝胶的仿生应用提供了切入点。反映这些方面,最近已经报道了关于各向异性水凝胶的越来越多的研究。
更新日期:2018-01-10
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