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IFN-Lambda: The Key to Norovirus’s Secret Hideaway
Cell Host & Microbe ( IF 20.6 ) Pub Date : 2017-10-11 , DOI: 10.1016/j.chom.2017.09.010
Sonja M. Best , Shelly J. Robertson

The cellular tropism of noroviruses in immune-competent hosts remains enigmatic. In recent studies in Cell Host & Microbe and Immunity, Lee et al. (2017) and Tomov et al. (2017) determine that norovirus innate immune evasion enables infection of intestinal epithelial cells, escape from adaptive immunity, virus persistence, and shedding.



中文翻译:

IFN-Lambda:诺如病毒秘密藏身之处的关键

诺曼病毒在具有免疫能力的宿主中的细胞嗜性仍然是谜。在《细胞宿主与微生物免疫》的最新研究中,Lee等人。(2017)和Tomov等。(2017)确定诺如病毒先天免疫逃避能够使肠道上皮细胞感染,逃避适应性免疫,病毒持久性和脱落。

更新日期:2017-10-11
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