The determinants of helminth resistance are not well understood. In this issue of Cell Host & Microbe, Entwistle et al. (2017) provide intriguing evidence that a phospholipase A2 (Pla2g1b) produced by epithelial cells can impair larval development in helminths, providing a novel mechanism contributing to intestinal nematode resistance.

中文翻译：

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Pla2g1b将蠕虫置于危险之中

蠕虫抵抗力的决定因素还没有被很好地理解。在本期《细胞宿主与微生物》中，Entwistle等人。（2017）提供了有趣的证据，即上皮细胞产生的磷脂酶A2（Pla2g1b）可以损害蠕虫的幼虫发育，提供了有助于肠道线虫抗性的新机制。