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Shigella Stays on the Move
Cell Host & Microbe ( IF 20.6 ) Pub Date : 2017-10-11 , DOI: 10.1016/j.chom.2017.09.013 Noelia Lopez-Montero , Jost Enninga
中文翻译:
志贺氏菌保持移动
更新日期:2017-10-11
Cell Host & Microbe ( IF 20.6 ) Pub Date : 2017-10-11 , DOI: 10.1016/j.chom.2017.09.013 Noelia Lopez-Montero , Jost Enninga
Guanylate-binding proteins (GBPs) confer protection against intracellular pathogens. In this issue of Cell Host & Microbe, Wandel et al. (2017) report that cytosolic Shigella becomes trapped within a GBP coat that prevents bacterial cell-to-cell spread. However, this defense mechanism is counteracted by the bacterial E3 ubiquitin ligase IpaH9.8.
中文翻译:
志贺氏菌保持移动
鸟苷酸结合蛋白(GBP)赋予针对细胞内病原体的保护作用。在本期《细胞宿主与微生物》中,Wandel等人。(2017)报告说,胞质志贺氏菌被困在GBP外套中,以防止细菌在细胞间扩散。但是,这种防御机制被细菌E3泛素连接酶IpaH9.8抵消。