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Efficacy and safety of once-monthly pasireotide in Cushing's disease: a 12 month clinical trial.
The Lancet ( IF 98.4 ) Pub Date : 2018-01-01 , DOI: 10.1016/s2213-8587(17)30326-1
André Lacroix , Feng Gu , Wilson Gallardo , Rosario Pivonello , Yerong Yu , Przemysław Witek , Marco Boscaro , Roberto Salvatori , Masanobu Yamada , Libuse Tauchmanova , Michael Roughton , Shoba Ravichandran , Stephan Petersenn , Beverly M K Biller , John Newell-Price , Giorgio Arnaldi , Hesarghatta Shyamasunder Asha , Tushar Bandgar , Ariel Barkan , Henrik Biering , Marie Bex , Marek Bolanowski , Marcello Delano Bronstein , Thierry Brue , Dario Bruera , Francesco Cavagnini , Abdurrahman Comlekci , Christophe De Block , Tuncay Delibasi , Carmen Fajardo-Montañana , Richard Abraham Feelders , Maria Fleseriu , Monica Roberto Gadelha , Eliza Brevoort Geer , Anthony Heaney , Ghislaine Houde , Atsuhiro Ichihara , Syed Ali Imran , Adriana Ioachimescu , Pinar Kadioglu , Yiming Li , Paola Loli , Mitsuru Nishiyama , Liudmila Rozhinskaya , Marek Ruchala , Youichi Saitoh , Christof Schöfl , Jochen Schopohl , Akira Shimatsu , Chikara Shimizu , Thiti Snabboon , Peter Snyder , Noriyuki Suzaki , Antoine Tabarin , Yutaka Takahashi , Susana Tara Britto , Guy T'Sjoen , Marie-Christine Vantyghem , Brigitte Velkeniers , Susan Webb , Shozo Yamada

Cushing's disease is a rare debilitating endocrine disorder for which few prospective interventional studies have been done. We report results of the first phase 3 trial assessing long-acting intramuscular pasireotide in patients with Cushing's disease.

中文翻译:

每月一次Pasireotide在库欣病中的疗效和安全性:一项为期12个月的临床试验。

库欣氏病是一种罕见的使人衰弱的内分泌疾病,对其进行的前瞻性干预研究很少。我们报告了评估库欣氏病患者中长效肌内帕瑞肽的第一个3期试验的结果。
更新日期:2017-12-20
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