In the present review, we present the history and future of texaphyrins, pentaaza Schiff base macrocycles with an expanded 5-coordination sphere, possessing chelation prowess of 24 different stable 1:1 complexes. Intrinsically unique photophysical and magnetic properties of metallotexaphyrins have enabled a broad spectrum of applications, resulting in multiple clinical phase trial evaluations of these compounds. The combination of texaphyrins with nanotechnology underscores the promising future of these materials, which aims to resolve inherent limitations of molecular counterparts in a nanovehicle.

中文翻译：

---

特沙弗林：从分子到纳米颗粒

在当前的审查中，我们介绍了具有扩展的5配位域，具有24种不同的稳定1：1配合物螯合能力的texaphyrins，pentaaza Schiff碱基大环化合物的历史和未来。金属硫卟啉的内在独特的光物理和磁特性使其具有广泛的应用范围，从而对这些化合物进行了多个临床阶段的试验评估。texaphyrins与纳米技术的结合强调了这些材料的有希望的未来，其目的是解决纳米车辆中分子对应物的固有局限性。