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GDF15 and energy balance: homing in on a mechanism
Nature Medicine ( IF 58.7 ) Pub Date : , DOI: 10.1038/nm.4414 Irene Cimino 1 , Anthony P Coll 1 , Giles S H Yeo 1
Nature Medicine ( IF 58.7 ) Pub Date : , DOI: 10.1038/nm.4414 Irene Cimino 1 , Anthony P Coll 1 , Giles S H Yeo 1
Affiliation
GDF15 and energy balance: homing in on a mechanism
中文翻译:
GDF15 和能量平衡:归位机制
GDF15 和能量平衡:归位机制
更新日期:2017-10-11
Nature Medicine, Published online: 6 October 2017; doi:10.1038/nm.4414
Three recent studies in mice have identified a specific receptor, GFRAL, for the known anorectic peptide GDF15. The finding increases mechanistic understanding of its effect and paves the way for the development of novel anti-obesity therapeutics.
中文翻译:
GDF15 和能量平衡:归位机制
GDF15 和能量平衡:归位机制
Nature Medicine,在线发布:2017 年 10 月 6 日;doi:10.1038/nm.4414
最近在小鼠中进行的三项研究已经确定了已知厌食肽 GDF15 的特异性受体 GFRAL。这一发现增加了对其作用的机制理解,并为开发新型抗肥胖疗法铺平了道路。