Evolution in the form of selective breeding has long been harnessed as a useful tool by humans. However, rapid evolution can also be a danger to our health and a stumbling block for biotechnology. Unwanted evolution can underlie the emergence of drug and pesticide resistance, cancer, and weeds. It makes live vaccines and engineered cells inherently unreliable and unpredictable, and therefore potentially unsafe. Yet, there are strategies that have been and can possibly be used to stop or slow many types of evolution. We review and classify existing population genetics-inspired methods for arresting evolution. Then, we discuss how genome editing techniques enable a radically new set of approaches to limit evolution.

长期以来，人类一直将选择育种形式的进化作为一种​​有用的工具。但是，快速发展也可能对我们的健康构成威胁，也是生物技术的绊脚石。有害的进化可能是药物和杀虫剂抗性，癌症和杂草出现的基础。它使活疫苗和工程细胞固有地不可靠，不可预测，因此潜在地不安全。但是，已经有并且可以用来阻止或减缓许多类型的进化的策略。我们审查和分类现有的人口遗传学启发的方法来阻止进化。然后，我们讨论了基因组编辑技术如何启用一套全新的方法来限制进化。