Background

Surface-enhanced Raman spectroscopy (SERS) techniques are becoming increasingly widespread and accessible for accurate and specific identification of chemical or microbiological contaminants in foodstuffs. However, the consistency and repeatability of SERS-based techniques is a challenge due to complicated detection environments. This drawback can be overcome by integrating the SERS detection into a microfluidic platform, which can provide a continuous flow condition for highly reproducible SERS measurements. Furthermore, the SERS-microfluidic platform can perform elaborating sample pre-treatments, showing great potentials for on-situ analysis of food contaminants.

Scope and approach

This review mainly summarizes the principles and methods of SERS-microfluidic systems, as well as their applications in rapid analysis of food contaminants. Three ways of integrating SERS substrate into microfluidic channels are highlighted. Finally, the main challenges and future efforts in developing SERS-microfluidic systems for on-situ food contaminants detection are discussed.

Key findings and conclusions

SERS-microfluidic platform conforms to the development tendency of modern analytical technology, and has great potentials for rapid analysis of food contaminants.

中文翻译：

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SERS-微流体系统：快速分析食品污染物的潜在平台

背景

表面增强拉曼光谱（SERS）技术正变得越来越普及，可用于准确，特异性地识别食品中的化学或微生物污染物。然而，由于复杂的检测环境，基于SERS的技术的一致性和可重复性是一个挑战。可以通过将SERS检测集成到微流体平台中来克服此缺点，该平台可以为高度可重复的SERS测量提供连续的流动条件。此外，SERS-微流体平台可以执行详尽的样品预处理，显示出对食品污染物进行现场分析的巨大潜力。

范围和方法

这篇综述主要总结了SERS-微流体系统的原理和方法，以及它们在食品污染物快速分析中的应用。重点介绍了将SERS底物整合到微流体通道中的三种方法。最后，讨论了开发用于现场食品污染物检测的SERS微流体系统的主要挑战和未来的努力。

主要发现和结论

SERS-微流控平台符合现代分析技术的发展趋势，具有快速分析食品污染物的巨大潜力。