A new method for synthesis of trifluoromethylated and pyrrolidinedione-fused pyrrolidines is developed through a three-component and decarboxylative [3 + 2] cycloaddition of non-stabilized N-unsubstituted azomethine ylides with commercially available trifluoroacetophenones. This efficient and economic synthesis only produces stoichiometric amount of CO₂ and H₂O as byproducts.

中文翻译：

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通过非稳定的N-未取代的偶氮甲亚胺的脱羧[3 + 2]环加成反应合成三氟甲基化的吡咯烷

通过将未稳定的N-未取代的偶氮甲亚胺与市场上可得的三氟苯乙酮进行三组分和脱羧[3 + 2]环加成反应，开发了一种新的合成三氟甲基化和吡咯烷二酮稠合的吡咯烷的方法。这种高效和经济的合成仅产生CO的化学计量量的₂和H ₂ O作为副产物。