The reason why some parasites specifically target the brain remains a mystery. Often, it is seen that the primary site of infection is quite remote from the brain, but an eventual involvement of the cerebral tissue is seen to occur that becomes the cause of death of the majority of the patients. In the absence of a clear preferential reason for targeting the brain, chemicals produced by the nervous system, which have miniature concentrations in the blood, appear to set up a chemical attraction that eventually causes them to migrate to the neural tissue. We studied the possible chemicals of neural origin that can lure the parasite toward the brain, enabling them to cause meningoencephalitis. The identification of these chemicals could be of enormous prophylactic significance as blocking the chemotaxis of neurotropic parasite by antagonist drugs and chemicals can prevent cerebral infection and provide ample time to eradicate the parasites at the primary site of infection.

中文翻译：

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脑中是否存在针对嗜神经性寄生虫的胆碱能生存诱因？

一些寄生虫专门针对大脑的原因仍然是个谜。通常，可以看到感染的主要部位离大脑很远，但是可以看到最终发生了脑组织受累，成为大多数患者死亡的原因。在没有明确的针对大脑的优先理由的情况下，血液中浓度极低的神经系统产生的化学物质似乎建立起化学吸引力，最终导致它们迁移至神经组织。我们研究了可能源自神经的化学物质，这些化学物质可将寄生虫引向大脑，从而引起脑膜脑炎。