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Trends on (elemental and molecular) mass spectrometry based strategies for speciation and metallomics
Trends in Analytical Chemistry ( IF 11.8 ) Pub Date : 2017-10-03 , DOI: 10.1016/j.trac.2017.09.025
M. Montes-Bayón , M. Sharar , M. Corte-Rodriguez

The capabilities of electrospray ionization (ESI) and matrix assisted laser desorption/ionization (MALDI) to permit species identification in combination with inductively coupled plasma (ICP) mass spectrometry to conduct element-tagged species monitoring have been exploited for a number of applications in speciation studies over the years. In this review, we report the new trends in the combined application of these techniques to address the structural and quantitative insights for different speciation/metallomics issues including the monitoring of natural elemental labels and drug metabolism products as well as the characterization of metallic nanoparticles and their corresponding metal ions. In addition, the trends on the analysis of trace elements in single cells by elemental MS together with the exponential growth of the imaging experiments, are also covered.



中文翻译:

基于(元素和分子)质谱的形态学和冶金学趋势

电喷雾电离(ESI)和基质辅助激光解吸/电离(MALDI)的能力允许物种识别与感应耦合等离子体(ICP)质谱结合进行元素标记的物种监测,已在物种形成中得到了许多应用多年来的研究。在这篇综述中,我们报告了这些技术联合应用的新趋势,以解决针对不同物种/金属学问题的结构和定量见解,包括监测天然元素标记和药物代谢产物以及表征金属纳米颗粒及其相应的金属离子。此外,还涵盖了通过元素MS分析单个细胞中痕量元素的趋势以及成像实验的指数增长。

更新日期:2018-07-08
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