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Vitamin D supplementation to prevent asthma exacerbations: a systematic review and meta-analysis of individual participant data.
The Lancet ( IF 98.4 ) Pub Date : 2017-11-01 , DOI: 10.1016/s2213-2600(17)30306-5
David A Jolliffe 1 , Lauren Greenberg 1 , Richard L Hooper 1 , Christopher J Griffiths 2 , Carlos A Camargo 3 , Conor P Kerley 4 , Megan E Jensen 5 , David Mauger 6 , Iwona Stelmach 7 , Mitsuyoshi Urashima 8 , Adrian R Martineau 2
Affiliation  

A previous aggregate data meta-analysis of randomised controlled trials showed that vitamin D supplementation reduces the rate of asthma exacerbations requiring treatment with systemic corticosteroids. Whether this effect is restricted to patients with low baseline vitamin D status is unknown.

中文翻译:


补充维生素 D 以预防哮喘恶化:对个体参与者数据的系统回顾和荟萃分析。



先前对随机对照试验的汇总数据荟萃分析表明,补充维生素 D 可降低需要全身皮质类固醇治疗的哮喘恶化率。这种效应是否仅限于基线维生素 D 状态较低的患者尚不清楚。
更新日期:2017-10-04
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